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DOI: 10.5146/tjpath.2018.01445
Spontaneous Regression of Primary Thyroid Lymphoma: Two Rarities at the Same Time
Francisco ILLÁN-GAMBÍN1, Pablo MANRESA-MANRESA2, Estefanía RODRÍGUEZ-ALEO3, Ignacio ARANDA-LÓPEZ1
1Department of Pathology, University General Hospital of Alicante, ALICANTE, SPAIN
2Department of Hematology, University General Hospital of Alicante, ALICANTE, SPAIN
3Nursing Department, University General Hospital of Alicante, ALICANTE, SPAIN
Keywords: Lymphoma, Thyroid neoplasms, Spontaneous neoplasm regression, PD-L1

Primary thyroid lymphomas are pretty uncommon, and constitute about 5% of the neoplasms of this organ. Spontaneous tumor regression is defined as the total or partial disappearance of a tumor as proven by microscope without treatment or under inadequate treatment. It is estimated to happen in one out of 60,000-100,000 cases. We present a case of primary thyroid lymphoma with spontaneous regression after diagnostic puncture and corroborated with hemithyroidectomy at four months. The patient died after twenty-six months of follow-up because of endocarditis and there was no relapse at any time.

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