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2012, Volume 28, Number 3, Page(s) 231-237
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DOI: 10.5146/tjpath.2012.01129 |
The Influence of Cervicovaginitis Agents on Epithelial Cell Changes: Comparison of Mardin City's Data with the Literature |
Işık İkbal BARIŞ1, Ayşe Nur KELEŞ2, Yeliz ARMAN KARAKAYA3 |
1Kadın Doğum ve Çocuk Hastanesi, Patoloji Bölümü, MARDİN, TÜRKİYE
2Dicle Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Dİyarbakır, TÜRKİYE
3Ege Doğumevi Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, İZMİR, TÜRKİYE1Department of Pathology, Maternity and Children's Hospital, MARDİN, TURKEY
2Department of Pathology, Dicle University, Faculty of Medicine, DİYARBAKIR, TURKEY
3Aegean Obstetrics Gynecology Training and Research Hospital, İZMİR, TURKEY |
Keywords:
Cervical smears, Uterine cervical dysplasia, Uterine cervicitis, Mardin |
Objective: The aim of this paper was to observe the reactive changes
of epithelial cells exposed to the influence of cervicovaginitis agents
that play an important role in the cytology practice and may cause an
exaggerated appearance.
Material and Method: 378 cases with cervicovaginitis caused by a
specific agent were compared with 100 control cases. It was recorded
if the inflammation had concomitant cellular changes and atypia or
not. After treatment, control smears were examined. The reactive and
atypical situations of the cells were considered after the treatment.
With the aid of the previous data, the answer to the following question
was searched: Is epithelial atypia a real event or a reactive atypia that
accompanies an existing cervicitis agent?
Results: In the first interpretation, Candida group had the
most frequent reactive and ASC-US (Atypic Squamous cells of
Undetermined Significance) changes (56,4% and 59,5% respectively).
The bacterial vaginosis and Trichomonas vaginalis groups showed
ASC-US rates of 25% and 9,5% respectively while in control group
the rate was 6,0%. After treatment, the number of cases of ASC-US
decreased from 50 to 11. Similarly, the number decreased from 21 to
10 in the bacterial vaginosis group.
Conclusion: Cervicovaginitis agents need more attention because
of their outcomes. Being aware of the cervicovaginitis agents during
interpretation is essential for preventing a false positive diagnosis and
unnecessary anxiety especially where cellular atypia is concerned.
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