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2015, Volume 31, Number 3, Page(s) 215-218     
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DOI: 10.5146/tjpath.2013.01215
Synchronous Primary Endometrial Carcinoma and Metastatic Malignant Melanoma in an Ovarian Cystic Teratoma
Mine GENÇ1, Oya SİVRİKOZ2, Berhan GENÇ3, Sefa KURT4, Esin ÇELİK1
1Department of Obstetric & Gynecology, Şifa University, Faculty of Medicine, İZMİR, TURKEY
2Department of Pathology, Şifa University, Faculty of Medicine, İZMİR, TURKEY
3Department of Radiology, Şifa University, Faculty of Medicine, İZMİR, TURKEY
4Department of Obstetric & Gynecology, Aegean Maternity and Women's Health Hospital, İZMİR, TURKEY
Keywords: Melanoma, Ovary, Teratoma, Endometrial neoplasms

Malignant transformation of a benign cystic teratoma of the ovary is only rarely seen. A review of the English literature revealed no reports of a malignant melanoma developing from concurrent primary endometrial carcinoma and ovarian cystic teratoma. We report herein a 54-year-old nulliparous woman who underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy for a pelvic mass and was diagnosed by histopathological examination to have a malignant melanoma developing from concurrent primary endometrial carcinoma and ovarian cystic teratoma. No foci of primary malignant melanoma except for the ovary were found upon clinical examination. The patient received postoperative interferon alpha 2B and radiotherapy. She was still asymptomatic at 12 months of follow-up.

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