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2016, Volume 32, Number 3, Page(s) 193-195     
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DOI: 10.5146/tjpath.2013.01217
Pulmonary Benign Metastasizing Leiomyoma: An Extremely Rare Case
Yetkin AĞAÇKIRAN1, Göktürk FINDIK2, Leyla N. ÜSTÜN2, Koray AYDOĞDU2, Sadi KAYA2
1Department of Pathology, Atatürk Chest Diseases and Thoracic Surgery Education and Research Hospital, ANKARA, TURKEY
2Department of Chest Surgery, Atatürk Chest Diseases and Thoracic Surgery Education and Research Hospital, ANKARA, TURKEY
Keywords: Leiomyoma, Uterus, Lung, Metastasis, Lymphatic

Benign metastasizing leiomyoma is typically seen in young premenopausal women after a mean period of 15 years following uterine leiomyoma or hysterectomy surgery. They are usually incidentally seen on chest x-rays and are nodular lesions that appear as bilateral nodules with a benign appearance and consist of smooth muscle proliferation. A 44-year-old female presented at her healthcare institution for backache for the last 9 months. Multiple nodules (largest 15 mm) scattered in both lungs and consistent with metastases were detected on computed tomography. The PET-CT results revealed multiple nodular densities with increased metabolic activity (SUVmax: 1.92) in both lungs, with the largest one measuring approximately 15 mm and located in the lower lobe superior segment of the right lung. A benign metastasizing leiomyoma was diagnosed with open wedge biopsy of the lung. We present this case due to its interesting clinical presentation and rarity and emphasize the pathogenesis.

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