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2017, Volume 33, Number 1, Page(s) 070-073     
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DOI: 10.5146/tjpath.2014.01253
Acinar Adenocarcinoma of Prostate with Predominant Ttf-1 Positive Intraductal Component
Banu SARSIK1, Nisar KARADENİZ1, Adnan ŞİMŞİR1, Rahmi AKYOL1, Kutsal YÖRÜKOĞLU2, Sait ŞEN1
1Department of Pathology, Ege University, Faculty of Medicine, İZMİR, TURKEY
2Dokuz Eylül University, Faculty of Medicine, İZMİR, TURKEY
Keywords: Prostate neoplasms, Ductal carcinoma, Thyroid transcription factor-1

Intraductal carcinoma of prostate has been previously described in radical prostatectomies. It’s rarely encountered in needle biopsies in the absence of infiltrative carcinoma. But, both histogenesis and nomenclature of the lesion is still controversial. Among the pure intraductal carcinoma of prostate cases, a different solid patern was described with smaller nuclei at the center of the ducts. However, there is a lack of information about the association of those cases with acinar prostate adenocarcinoma. Herein, we describe a case of acinar adenocarcinoma with predominant non-neuroendocrine TTF-1 positive small cell intraductal component.

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