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2017, Volume 33, Number 3, Page(s) 256-258     
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DOI: 10.5146/tjpath.2014.01276
Mandibular Actinomyces Infection Mimicking a Malignancy: Case Report
Gülay BULUT1, Yasemin BAYRAM2, Mehmet Deniz BULUT3, Mehmet Fatih GARÇA4, İrfan BAYRAM1
1Departments of Pathology, Yüzüncü Yıl University, Faculty of Medicine, VAN, TURKEY
2Departments of Microbiology, Yüzüncü Yıl University, Faculty of Medicine, VAN, TURKEY
3Departments of Radiology, Yüzüncü Yıl University, Faculty of Medicine, VAN, TURKEY
4Departments of Otorhinolaryngology, Yüzüncü Yıl University, Faculty of Medicine, VAN, TURKEY
Keywords: Cervicofacial actinomycosis, Pathology, Mandible

Actinomycosis is a rare, chronic, suppurative and granulomatous disease caused by Actinomyces israelii, which is a filamentous, anaerobic, gram-positive, saprophytic organism in the oral cavity. Diagnosis of actinomycosis depends on positive culture or identification of Actinomyces colonies and sulfur granules in histological specimens. In our case, a mass had been growing in the mandible for eight months. The mass appeared to be malignant, both clinically and radiologically. A histopathological examination of the mandible revealed actinomycosis. It should be noted that actinomycosis can mimic a malignancy, and for differential diagnosis, bone biopsy or fine-needle aspiration should be performed pre-operatively.

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