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2020, Volume 36, Number 3, Page(s) 179-187     
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DOI: 10.5146/tjpath.2020.01488
How to Set Up a Molecular Pathology Lab: A Guide for Pathologists
Anıl AYSAL, Burçin PEHLIVANOĞLU, Sümeyye EKMEKCI, Betül GÜNDOĞDU
Department of Molecular Pathology, Dokuz Eylul University, Graduate School of Health Sciences, IZMIR, TURKEY
Keywords: Molecular pathology laboratory, Laboratory setup, Guide

In today’s pathology practice, pathologists combine molecular tests with conventional histopathological methods. Pathology laboratories should therefore be designed and operated in accordance with the requirements of molecular testing procedures. While the specifics of the requirements may vary depending on the spectrum of the tests that will be performed, there are several basic criteria that need to be fulfilled for standardization. Adequate space, appropriate equipment and qualified personnel are required to establish a molecular pathology laboratory. One of the most important points that should be taken into consideration while designing a molecular pathology laboratory is to create a plan to prevent contamination. As molecular diagnosis has a major role in treatment decisions, the management of the molecular pathology laboratory is of utmost importance. In this review, the criteria required to establish an optimal molecular pathology laboratory will be reviewed.

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