SCImago Journal & Country Rank
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE)
2001, Volume 17, Number 1-2, Page(s) 011-013     
[ Abstract (Turkish) ] [ PDF ]
PLACENTAL IRON DEPOSITION AND SIGNIFICANCE IN THE FETAL ANOMALIES AND MOLAR PREGNANCIES:
Levent YILDIZ, Oğuz AYDIN, Kamile KURT, Sancar BARIŞ, Filiz KARAGÖZ, Bedri KANDEMİR
Ondokuz Mayıs Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı, Samsun

Classical studies on placental histochemistry revealed linear iron deposits in the placenta of normal first half gestation. These studies described normal third-trimester placentas lacking this type of deposits. In this study 22 normal term placentas, 15 first trimester placentas of undesired pregnancy, 11 from pregnancies associated with fetal anomalies, and 17 placentas of molar pregnancies were examined by Perl’s Prussian Blue for iron deposits in light microscope. In normal first trimester and terminal pregnancies, the placental iron deposits are present as linear granular deposits in the trophoblastic basement membrane (% 6.60 and %13.60 of cases, respectively, and average percentage of affected villi was %5 and %8 respectively). In the presence of fetal anomalies, the iron deposition is markedly increased in the trophoblastic basement membrane (%45.50 of cases). In these cases average percentage of villus involvement was %42.40. There was no iron deposits in the molar pregnancies. It is concluded that granular iron deposits in the trophoblastic basement membrane are normally present, gradually decreasing in the progress of normal pregnancies. Increased iron deposit in the placenta is a pathologic finding and may be associated with fetal anomalies.

[ Abstarct (Turkish) ] [ PDF ]