Tavassoli, F, Eusebi V: ARP Press, Silver Spring, Maryland, May 2009, 418 pp, €147.45
Contents: Normal Anatomy * Benign Lesions * Lobular Intraepithelial Neoplasia * Ductal Intraepithelial
Neoplasia * Papillary Lesions of the Breast * Microinvasive Carcinoma * Staging of Breast Carcinoma and
Prognostic and Predictive Indicators * Major Variants of Carcinoma * Carcinomas of Low-Grade Malignancy *
Uncommon Variants of Carcinoma * Myoepithelial Lesions * Benign Soft Tissue Lesions * Sarcomas * Biphasic
Tumors * Diseases of the Nipple * Lymphoid and Hematopoietic Lesions * Male Breast Lesions * Metastases to
the Breast from Nonmammary Neoplasms.
“Tumors of the Mammary Gland” written by Fattaneh Tavassoli
and Vincenzo Eusebi, well- known experts of the breast
pathology is about to be presented to the use of pathologists.
This new book of “Atlas of Tumor Pathology” series published
by AFIP will draw the attentions of both the specialists dealing
with surgical pathology, and those specifically working on the
pathology of the breast.
This tenth book of the fourth AFIP series, printed hard cover,
is composed of 18 chapters, appendix, and contents sections.
All illustrations in this 418 paged book are full-colored.
Describing the subjects in a brief, and comprehensible form,
this atlas will take its place on microscopy desktop of the
pathologists. The distribution of subjects is also well-balanced
in this atlas comprising 474 figures, some of which including
more than one photograph.
As will be expected, ductal proliferative lesions and in situ
ductal carcinomas are evaluated according to Tavassoli's DIN
terminology, and both in the headings and in the text, DIN is
used in association with the classical terminology. This section
provides an update of Dr Tavassoli's current approach in a book
chapter, and moreover give the readers a chance to understand
the proposed differences compared to WHO classification.
“Benign tumors of soft tissue” and “sarcomas” are intriguing
chapters. Lesions except those with typical and single way of
differentiation such as liposarcoma, osteosarcoma, leiomyoma,
schwannoma are explained in a simple terminology. Authors
classify benign soft tissue lesions with a multidirectional
differentiation capacity as “benign stromal spindle cell tumors,
BSSCT”. They subcategorize these tumors into “BSSCT with
predominant myofibroblastic differentiation”, “BSSCT with
predominant adipocytic component” (spindle cell lipoma),
and “BSSCT with predominant fibroblastic component”
(solitary fibrous tumor, hemangiopericytoma). Sarcomas
are termed “malignant stromal cell tumors” and subgrouped as “tumors with predominant fibroblastic differentiation
(fibrosarcoma, malignant fibrous histiocytoma)” and those
“tumors with predominant myofibroblastic differentiation
(malignant myofibroblastoma, myofibrosarcoma)”. This
terminology provides an easy approach to these lesions which
pose diagnostic difficulties for pathologists because of their
multifaced appearance. Both chapters are the richest parts of
the book in respect to microscopic photographs.
Breast carcinomas are discussed in three categories: Major
types (including invasive ductal-NOS, and invasive lobular
carcinomas), low grade carcinomas, and rare carcinomas. As
in the other chapters things to be said are given in a brief and
comprehensive way, answers are provided to the questions in
the mind of general and breast pathologists. The definitions
of tumor types, alternative terminologies, macroscopic,
microscopic and in most of them cytologic findings are
given in detail; up-to-date information about prognosis and
treatment is mentioned.
In the appendix, subjects of thin needle aspiration biopsy and
core biopsy are mentioned in detail, macro-section technique is
also explained, and synoptic reporting proposal of Association
of Directors of Anatomic and Surgical Pathology (ADASP) is
In conclusion, “Tumors of the Mammary Gland” is an
important book directed to morphology of breast lesions.
Morphology of several lesions, encountered during routine
practice, are explained in a brief form; considering the size of
the book a great number of demonstrative photographs, all
full-colored, are given.
Describing the subjects in a simple, comprehensible and brief
form, this book will be an important information source, and
a guide book for both general and breast pathologists in the
way to diagnosis.