Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2015, Vol 31, Num, 3     (Pages: 215-218)

Synchronous Primary Endometrial Carcinoma and Metastatic Malignant Melanoma in an Ovarian Cystic Teratoma

Mine GENÇ 1, Oya SİVRİKOZ 2, Berhan GENÇ 3, Sefa KURT 4, Esin ÇELİK 1

1 Department of Obstetric & Gynecology, Şifa University, Faculty of Medicine, İZMİR, TURKEY
2 Department of Pathology, Şifa University, Faculty of Medicine, İZMİR, TURKEY
3 Department of Radiology, Şifa University, Faculty of Medicine, İZMİR, TURKEY
4 Department of Obstetric & Gynecology, Aegean Maternity and Women's Health Hospital, İZMİR, TURKEY

DOI: 10.5146/tjpath.2013.01215
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Malignant transformation of a benign cystic teratoma of the ovary is only rarely seen. A review of the English literature revealed no reports of a malignant melanoma developing from concurrent primary endometrial carcinoma and ovarian cystic teratoma. We report herein a 54-year-old nulliparous woman who underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy for a pelvic mass and was diagnosed by histopathological examination to have a malignant melanoma developing from concurrent primary endometrial carcinoma and ovarian cystic teratoma. No foci of primary malignant melanoma except for the ovary were found upon clinical examination. The patient received postoperative interferon alpha 2B and radiotherapy. She was still asymptomatic at 12 months of follow-up.

Keywords : Melanoma, Ovary, Teratoma, Endometrial neoplasms