Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2020, Vol 36, Num, 2     (Pages: 164-168)

Spontaneous Regression of Primary Thyroid Lymphoma: Two Rarities at the Same Time

Francisco ILLÁN-GAMBÍN 1, Pablo MANRESA-MANRESA 2, Estefanía RODRÍGUEZ-ALEO 3, Ignacio ARANDA-LÓPEZ 1

1 Department of Pathology, University General Hospital of Alicante, ALICANTE, SPAIN
2 Department of Hematology, University General Hospital of Alicante, ALICANTE, SPAIN
3 Nursing Department, University General Hospital of Alicante, ALICANTE, SPAIN

DOI: 10.5146/tjpath.2018.01445
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Primary thyroid lymphomas are pretty uncommon, and constitute about 5% of the neoplasms of this organ. Spontaneous tumor regression is defined as the total or partial disappearance of a tumor as proven by microscope without treatment or under inadequate treatment. It is estimated to happen in one out of 60,000-100,000 cases. We present a case of primary thyroid lymphoma with spontaneous regression after diagnostic puncture and corroborated with hemithyroidectomy at four months. The patient died after twenty-six months of follow-up because of endocarditis and there was no relapse at any time.

Keywords : Lymphoma, Thyroid neoplasms, Spontaneous neoplasm regression, PD-L1