In this report, five uncommon soft tissue tumors with controversial histogenesis were reviewed. These were the low grade fibromyxoid sarcoma, acral myxoinflammatory fibroblastic sarcoma, pleomorphic hyalinizing angiectatic tumor, ossifying tumor of soft tissue and angiomatoid fibrous histiocytoma. These uncommon tumors often had been diagnosed incorrect, so their therapy delayed. All these tumors had an indistinct biological potential and unknown histogenesis