Parallel to the development in the fetal medicine and the prenatal diagnostic methods, the number of autopsies for stillbirths and neonatal deaths gradually increases. The pathological examination of the placenta is a complementary component for perinatal autopsy which can not be given up. Systemic diseases of mother that occurs before or during pregnancy cause various pathologies or make them more severe. In this study, the pathologies determined from the 190 placenta supplied from the Perinatal Research and Application Center of our faculty are presented. Of the 190 placenta examinated 48 inflamatuar case (25.6 %), 40 multifocal infarct (21%), 40 inter and perivillous fibrin deposition (21 %), 133 multifocal calcification (70 %), 21 increased syncytial knots (11 %), 18 umblical cord pathology (9.47 %), 4 chorangiomas (2.1 %), one basal plate hematoma (0.52 %), one placentomegaly (0.52 %) were identified. No pathology was determined in the remaining 21 (11.5 %) placentas. The pathological findings identified from placenta were correlated with the history of the mother and the fetus. Some of the pathologies determined in the placenta were noticed to be increased in diseases such as hypertension, eclampsy, diabetes mellitus of mothers and the autopsied fetus.