Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Ankara Patoloji Bülteni Archive

2001, Vol 18, Num, 2     (Pages: 007-010)

Basal cell adenomas of salivary glands

Önder Bozdoğan1, Pınar Atasoy1, Nazan Bozdoğan2

1Kırkkale Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı, KIRIKKALE
2Kırıkkale Devlet Hastanesi Patoloji Bölümü, KIRIKKALE

Basal cell adenomas are benign salivary gland neoplasms, which composed of basaloid cells and lack myxochondroid stroma. In this study, we evaluated the histopathological and immunhistochemical features of these rare tumours. Histopathological slides of 6 patient diagnosed as basal cell adenoma between 1997-1999 in pathology division of Johannes Gutenberg University Medical Faculty was retrospectively reviewed. All cases were stained with PAS, smooth muscle actin (SMA) and S-100. Basal cell adenomas comprised 2,8% of all parotid gland tumours. Four of the lesions were located in the right parotid gland and the remaining two were in the left parotid .The mean age of the patients was 60 years and the male to female ratio was 1/2. Two cases each were diagnosed as solid and trabeculotubular and one each of the remaining were tubular and membranous histology. One of the patients with trabeculolotubular morphology had spindle cell area suggesting myoepithelial differentiation. Immunhistochemical examination showed S-100 staining in all and SMA positivity in 5 of the cases. We thought that positive staining with S-100 and especially SMA showed the myoepitheilal cells in BHA. Our findings support the opinion that myoepithelial cells contribute to the formation of basal cell adenomas on which there has long been a controversy.

Keywords : Bazal hücreli adenom, tükrük bezi, S-100, Düz kas aktini,myoepitelyal hücreler, Basal cell adenoma, Salivary gland, S-100, Smooth muscle actin, Myoepithelial cells