Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Ankara Patoloji Bülteni Archive

2001, Vol 18, Num, 3     (Pages: 026-032)

The assessment of histopathological features in endometrial hyperplasia and carcinoma

Sema Bircan1, Sibel Öztürk1, Nural Erdoğan1, Arzu Ensari1, İlkkan Dünder2, Fırat Ortaç2

1Ankara Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı, ANKARA
2Ankara Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim Dalı,ANKARA


Endometrial carcinoma is the most common tumor of female genital tract. The stage at the time of diagnosis reflects extent of the tumor. In the FIGO staging system which determines the treatment and prognosis, the uterine and extrauterine histopathological parameters that show the natural spread pattern of the disease have been standardized. In this study, 38 hyperplasias and 32 endometrial carcinomas were evaluated retrospectively. In the evaluation of the carcinoma cases, the classification of World Health Organization was used, surgical-pathological staging was done. Hyperplasia cases were classified according to Kurman and Norris. Most carcinoma cases (29 cases) were endometrioid type and hyperplasia accompanied the tumors in 12 cases. An significant inverse correlation was found between the hyperplasia and myometrial invasion (p<0.05). The elderly patients had high-grade tumors (p<0.05). It was observed that myometrial invasion was correlated with menopausal state; the patients having invasion were concentrated in the postmenopausal period (p<0.05). In conclusion, while the depth of invasion, with or without concomitant hyperplasia, and histopathologic subtypes were determined as important factors, the patients ages and menopausal status could also be regarded as important clinical parameters in endometrial carcinoma.

Keywords : Endometrial karsinom, histopatolojik özellikler, endometrial carcinoma, histopathologic features