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2012, Volume 28, Number 2, Page(s) 181-183     
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DOI: 10.5146/tjpath.2012.01122
A Case of Pure Endophytic Squamous Cell Carcinoma of the Gallbladder: A Rare Entity with Aggressive Behaviour
Nazoora KHAN1, Nishat AFROZ1, Nazima HAIDER1, Mohammad Amanullah KHAN1,2
1Department of Pathology, Jawahar Lal Nehru Medical College, Aligarh Muslim University, ALIGARH, INDIA
2Department of Surgery, Jawahar Lal Nehru Medical College, Aligarh Muslim University, ALIGARH, INDIA
Keywords: Squamous cell carcinoma, Gallbladder, Differential diagnosis

Pure squamous cell carcinoma of gallbladder is a rare tumor accounting for only 3% of the malignancies of gallbladder. A 35-yearold female presented with pain and lump in right hypochondrium. Ultrasonography and computed tomography revealed a thickened gallbladder filled with stones without any obvious growth and a large hepatic mass. Histologically, a pure type of well differentiated squamous cell carcinoma of gallbladder was diagnosed after excluding all possible differential diagnoses owing to different histogenesis and aggressive biological behaviour. Early diagnosis is the most important parameter for improving the survival indices among the patients with squamous cell carcinoma of the gallbladder.

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