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2013, Volume 29, Number 2, Page(s) 160-163
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DOI: 10.5146/tjpath.2013.01170 |
Atypical Teratoid Rhabdoid Tumor: Case Report |
Fatma MARKOÇ1, Reşid Doğan KÖSEOĞLU1, Faik Alev DERESOY1, Ayşe Burcu ARIKAN1, Fatih Ersay DENİZ2, Erol ÖKSÜZ2 |
1Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Patoloji, Anabilim Dalı, TOKAT, TÜRKİYE
2Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Nöroşirurji Anabilim Dalı, TOKAT, TÜRKİYE
1Department of Pathology, Gaziosmanpaşa University, Faculty of Medicine, TOKAT, TURKEY
2Department of Neurosurgery, Gaziosmanpaşa University, Faculty of Medicine, TOKAT, TURKEY |
Keywords:
Brain tumors, Differential diagnosis |
Atypical teratoid rhabdoid tumor is a rare highly malignant
embryonal tumor of the central nervous system that is often seen in
early childhood. It is very important to distinguish it from other brain
tumors because it has a very poor prognosis and there are differences
in its treatment. A case of atypical teratoid rhabdoid tumor in a
six-week-old male baby is presented. The tumor was located at
posterior fossa. Histopathologically, the tumor has rhabdoid tumor
cells and mesenchymal components beside the undifferentiated small
cells. While EMA, vimentin, synaptophysin and smooth muscle actin
have been stained with immunohistochemical staining, desmin,
chromogranin, CD 99 and CD 56 have not been stained. The patient
died four months after surgery despite the chemotherapy given. In
conclusion, morphological characteristics can vary to a large extent
that it is difficult to recognize atypical teratoid rhabdoid tumor.
Immunohistochemical panel and molecular genetic study will help to
establish the correct diagnosis.
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