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2013, Volume 29, Number 2, Page(s) 160-163     
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DOI: 10.5146/tjpath.2013.01170
Atypical Teratoid Rhabdoid Tumor: Case Report
Fatma MARKOÇ1, Reşid Doğan KÖSEOĞLU1, Faik Alev DERESOY1, Ayşe Burcu ARIKAN1, Fatih Ersay DENİZ2, Erol ÖKSÜZ2
1Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Patoloji, Anabilim Dalı, TOKAT, TÜRKİYE
2Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Nöroşirurji Anabilim Dalı, TOKAT, TÜRKİYE
1Department of Pathology, Gaziosmanpaşa University, Faculty of Medicine, TOKAT, TURKEY
2Department of Neurosurgery, Gaziosmanpaşa University, Faculty of Medicine, TOKAT, TURKEY
Keywords: Brain tumors, Differential diagnosis

Atypical teratoid rhabdoid tumor is a rare highly malignant embryonal tumor of the central nervous system that is often seen in early childhood. It is very important to distinguish it from other brain tumors because it has a very poor prognosis and there are differences in its treatment. A case of atypical teratoid rhabdoid tumor in a six-week-old male baby is presented. The tumor was located at posterior fossa. Histopathologically, the tumor has rhabdoid tumor cells and mesenchymal components beside the undifferentiated small cells. While EMA, vimentin, synaptophysin and smooth muscle actin have been stained with immunohistochemical staining, desmin, chromogranin, CD 99 and CD 56 have not been stained. The patient died four months after surgery despite the chemotherapy given. In conclusion, morphological characteristics can vary to a large extent that it is difficult to recognize atypical teratoid rhabdoid tumor. Immunohistochemical panel and molecular genetic study will help to establish the correct diagnosis.

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