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2014, Volume 30, Number 1, Page(s) 069-072     
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DOI: 10.5146/tjpath.2013.01201
Seminoma Presenting as a Polypoid Bladder Mass: A Case Report
Afaf ALSOLAMİ1, Mohammed ALOTAİBİ2, Shouki BAZARBASHİ3, Abdulmonem ALMUTAWA4, Mohammed AKHTAR4
1Department of Pathology and Laboratory Medicine, King Khalid University Hospital, RIYADH, KINGDOM of SAUDI ARABIA
2Departments of Urology, King Faisal Specialist Hospital and Research Centre, Riyadh, KINGDOM of SAUDI ARABIA
3Departments of Medical Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, KINGDOM of SAUDI ARABIA
4 Departments of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, KINGDOM of SAUDI ARABIA
Keywords: Seminoma, Urinary bladder, Germ cell tumors, Hematuria

We report a case of extragonadal seminoma presenting as a polypoid mass in the urinary bladder. The patient presented with two months history of hematuria. Evaluation by CT scan and cystoscopic examination revealed a polypoid mass in the base of the bladder. Biopsy of the mass revealed a classical type of seminoma. The diagnosis of seminoma was supported by strong immunostaining of the tumor cells for C-Kit and placental alkaline phosphatase. Thorough physical examination and radiologic imaging of other organ systems failed to reveal any other tumor. Both testes were found to be normal on examination and on ultrasound imaging. Patient responded well to chemotherapy. This case is unique because to the best of our knowledge there are no previously reported cases in the literature with seminoma presenting as a bladder mass.

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