Ovarian Yolk Sac Tumor with Granulomatous Reaction Resembling Tuberculosis – A Unique Presentation

Shaista VASENWALA; Noor Afshan SABZPOSH; Hena ANSARI; Nazima HAIDER; Shazia PARVEEN; Murad AHMED

doi:10.5146/tjpath.2014.01229

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2016, Volume 32, Number 2, Page(s) 126-129

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DOI: 10.5146/tjpath.2014.01229

Ovarian Yolk Sac Tumor with Granulomatous Reaction Resembling Tuberculosis – A Unique Presentation

Shaista VASENWALA¹, Noor Afshan SABZPOSH², Hena ANSARI¹, Nazima HAIDER¹, Shazia PARVEEN², Murad AHMED¹

¹Department of Pathology, Jawaharlal Nehru Medical College, AMU, ALIGARH, INDIA
²Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, AMU, ALIGARH, INDIA

Keywords: Ovary, Germ cell tumor, Granuloma, Giant cells

Yolk sac tumors (endodermal sinus tumors) are an important subgroup of germ cell tumors of the ovary. They are seen in young females and are highly aggressive, but respond well to treatment. Although different morphological patterns can be seen on light microscopy, granulomatous reaction and giant cells are a very rare occurrence. We report the case of a young female with ovarian yolk-sac tumor in which a widespread granulomatous reaction was seen, causing a diagnostic dilemma.

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