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2017, Volume 33, Number 2, Page(s) 168-170
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DOI: 10.5146/tjpath.2014.01290 |
Malignant Melanoma Presenting as a Mediastinal Malignant Melanoma Presenting as a Mediastinal Unknown Primary Origin? |
Mukta PUJANI1, Mohd Jaseem HASSAN1, Sujata JETLEY1, Prabhat Kumar RAINA2, Mukesh KUMAR3 |
1Department of Pathology, Hamdard Institute of Medical Sciences & Research, NEW DELHI, INDIA
2Department of Surgery, Hamdard Institute of Medical Sciences & Research, NEW DELHI, INDIA
3Department of Radiology, Hamdard Institute of Medical Sciences & Research, NEW DELHI, INDIA |
Keywords:
Malignant melanoma, Neoplasm of unknown primary, Mediastinal neoplasm |
The most common site of primary malignant melanoma is the skin,
however, virtually any organ system may be involved. Metastatic
melanoma of unknown primary origin accounts for approximately
2-6% of all melanoma cases. The mediastinum as the site for malignant
melanoma is extremely rare, both as a primary or metastatic lesion.
Primary malignant melanoma of mediastinum is very rare with only
a handful of reports in the literature. We hereby report a rare case
of malignant melanoma of mediastinum in a 31 year old male who
was initially misdiagnosed on fine needle aspiration cytology as
adenocarcinoma for which he received chemotherapy with clinical
deterioration. Even on extensive meticulous search, no primary was
discovered.
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