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2017, Volume 33, Number 3, Page(s) 262-267
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DOI: 10.5146/tjpath.2014.01299 |
Benign Malformative Lesion of the Skull: Hamartoma with Ectopic Elements or Choristoma? |
Ece MERAM1, Hakan KARABAĞLI2, Christine GLASTONBURY3, Tarik TİHAN1, Pınar KARABAĞLI4 |
1Department of Pathology, UCSF, SAN FRANCISCO, USA
2Department of Neurosurgery, Selçuk University Faculty of Medicine, KONYA, TURKEY
3Department of Radiology, UCSF, SAN FRANCISCO, USA
4Department of Pathology, Selçuk University Faculty of Medicine, KONYA, TURKEY |
Keywords:
Hamartoma, Choristoma, Ectopic tissue, Heterotopic tissue, Skull |
Hamartoma and choristoma are terms that describe non-neoplastic,
mass-forming malformative lesions. Although each lesion has a
different composition, they have been used interchangeably in many
reports, especially for malformative lesions containing ectopic or
heterologous elements. We report a three month-old girl who was
brought to the clinic with a mass lesion at the posterior fontanel,
composed of predominantly osteo-cartilaginous tissue admixed
with skeletal muscle, peripheral nerve tissue, and ganglion. The
mass was resected completely. The composition of this benign lesion
with ectopic elements was consistent with an osteo-cartilaginous
hamartoma. We discuss the biological and clinical aspects such
malformative lesions within the skull to highlight the inconsistencies
of the nomenclature used in the literature.
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