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2020, Volume 36, Number 1, Page(s) 068-072     
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DOI: 10.5146/tjpath.2017.01416
Renal Microsporidiosis in Pediatric Bone Marrow Transplant Recipients: A Case Series
Saloni SHAH1, Sheba Sweetline JACOB1, Rama MANI1, Ashok PARAMESWARAN1, Sunil KUMAR1, Rajeev A ANNIGERI2, Raja MAHESH2, Ramya UPPULURI3
1Department of Histopathology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA
2Department of Nephrology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA
3Department of Hematology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA
Keywords: Kidney, Microsporidiosis, Opportunistic infection, Pediatrics, Bone marrow transplantation

Microsporidiosis is a rare, but emerging opportunistic infection in solid organ transplant and stem cell transplant recipients. Renal involvement in microsporidiosis is very rarely seen in these recipients. We describe two cases of pediatric renal microsporidiosis, diagnosed on renal biopsies, following bone marrow transplantation presenting as severe acute kidney injury. The first patient died, whereas the second survived due to early diagnosis based on high index of suspicion and prompt treatment with Albendazole. We believe these are the first such reported cases of renal microsporidiosis in pediatric bone marrow transplant recipients.

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