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2021, Volume 37, Number 3, Page(s) 249-253
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DOI: 10.5146/tjpath.2020.01517 |
Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature |
Sevda AKYOL1, Fatma OZ ATALAY2 |
1Department of Pathology, Hakkari Yuksekova State Hospital, HAKKARI, TURKEY 2Department of Bursa Uludag University Medicine Faculty, BURSA, TURKEY |
Keywords:
Myeloid sarcoma, Ovary, Female genital neoplasms |
Myeloid sarcoma (granulocytic sarcoma or chloroma) is a tumor formed by myeloid precursor cells in any localization other than the bone
marrow. It can occur without underlying acute myeloid leukemia (AML) or other myeloid neoplasms. Herein, we present a forty-two-year-old
female patient who underwent surgery because of a left adnexal mass. Microscopic examination of the specimen revealed cord-like arrangement
of the tumor cells with a diffuse growth of small blue cells effacing the ovarian stroma. Adult granulosa cell tumor was in the differential given the
scanty cytoplasm of the tumor and in fact was the diagnosis of the referring institution. Further microscopic evaluation with immunohistochemical
analysis at our institution revised the diagnosis to myeloid sarcoma. Myeloid sarcoma is a difficult tumor to diagnose due to its rarity, especially
in the absence of a history of leukemia, and correct tissue diagnosis is essential for its treatment.
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