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2022, Volume 38, Number 2, Page(s) 153-157     
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DOI: 10.5146/tjpath.2021.01543
Pleomorphic Adenoma of Breast: Report of Two Cases, One in A Male Patient
Orwa ELAIWY, Khaled AL-SAWALMEH, Hayan ABO SAMRA, Abdulrazzaq HAIDER, Mohammed AKHTAR
Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, DOHA, QATAR
Keywords: Pleomorphic adenoma, Breast, Male breast, Cartilage, Papilloma

Pleomorphic adenoma of breast (PAB) is a rare mammary tumor of a mixed epithelial-myoepithelial nature. We report two patients with PAB, one of which is male. We believe our male patient is the sixth case of PAB in male breast in the literature. The two cases expressed heterogeneous clinical and radiological characteristics while showing similar histology and immunohistochemical staining profile. The first case was managed with surgical resection while the second underwent interventional radiology excision. PAB is usually a benign entity with occasional cases of recurrence. Malignant transformation is rare but has been reported in a few cases.

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