Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2001, Vol 17, Num, 3-4     (Pages: 085-086)

EOSINOPHILIC ULCER OF THE ORAL MUCOSA : RIGA-FEDE DISEASE.

BİTİREN Muharrem 1, GÜREL Mehmet S. 2, ÖZARDALI H. İlyas 1

1 Harran Üniversitesi Tıp Fakültesi Patoloji AD, Şanlıurfa
2 Harran Üniversitesi Tıp Fakültesi Dermatoloji AD, Şanlıurfa

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Summary

Eosinophilic ulcer of the oral mucosa is an uncommon reactive lesion. It develops rapidly and usually heals spontaneously within several weeks. Mucosal trauma and local immune reaction are possible pathogenetic mechanisms. Microscopically, there is dense inflammatory cell infiltration of numerous eosinophils with lymphocytes and plasmocytes in the submucosa. Since it often mimics many oral malignancies and chronic disorders, the differential diagnosis is important. In this study, we report a case of eosinophilic ulcer of the oral mucosa with sublingual localisation in an eleven months old infant, and discuss its clinical and histopathological characteristics in the light of the literature.
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