Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2014, Vol 30, Num, 1     (Pages: 069-072)

Seminoma Presenting as a Polypoid Bladder Mass: A Case Report

Afaf ALSOLAMİ 1, Mohammed ALOTAİBİ 2, Shouki BAZARBASHİ 3, Abdulmonem ALMUTAWA 4, Mohammed AKHTAR 4

1 Department of Pathology and Laboratory Medicine, King Khalid University Hospital, RIYADH, KINGDOM of SAUDI ARABIA
2 Departments of Urology, King Faisal Specialist Hospital and Research Centre, Riyadh, KINGDOM of SAUDI ARABIA
3 Departments of Medical Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, KINGDOM of SAUDI ARABIA
4 Departments of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, KINGDOM of SAUDI ARABIA

DOI: 10.5146/tjpath.2013.01201
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We report a case of extragonadal seminoma presenting as a polypoid mass in the urinary bladder. The patient presented with two months history of hematuria. Evaluation by CT scan and cystoscopic examination revealed a polypoid mass in the base of the bladder. Biopsy of the mass revealed a classical type of seminoma. The diagnosis of seminoma was supported by strong immunostaining of the tumor cells for C-Kit and placental alkaline phosphatase. Thorough physical examination and radiologic imaging of other organ systems failed to reveal any other tumor. Both testes were found to be normal on examination and on ultrasound imaging. Patient responded well to chemotherapy. This case is unique because to the best of our knowledge there are no previously reported cases in the literature with seminoma presenting as a bladder mass.

Keywords : Seminoma, Urinary bladder, Germ cell tumors, Hematuria