Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2004, Vol 20, Num, 3-4     (Pages: 069-072)

ALVEOLAR SOFT PART SARCOMA: REPORT OF THREE CASES

METE Özgür 1, BİLGİÇ Bilge 1, DEMİRYONT Misten 1, ÖZGER Harzem 2, BAŞARAN Mert 3, AĞAOĞLU Fulya 3

1 İstanbul Üniversitesi, Istanbul Tıp Fakültesi, Patoloji ABD, İstanbul
2 İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Ortopedi ve Travmatoloji ABD, İstanbul
3 İstanbul Üniversitesi, Onkoloji Enstitüsü, İstanbul

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Alveolar soft part sarcoma is a rare soft tissue sarcoma of unknown histoge-nesis. It is most prevalent between 15-35 years of age and located in the lower extremities. As metastasis may occur as late as 30 years, patients should be followed up for a long time. Two cases presenting different survival features and one case with an interesting histomorphologic finding, which contained laminated calcifying bodies (psammoma bodies) were presented in this study. Desmin and CD56 were negative in all 3 patients. MyoD1 positivity was observed as cytoplasmic staining in only one case. The patient who died after 2 years following the resection of the primary tumour had a higher (10%) Kİ67 index whereas the other two patients had lower Kİ67 index (4%).

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