Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2017, Vol 33, Num, 1     (Pages: 070-073)

Acinar Adenocarcinoma of Prostate with Predominant Ttf-1 Positive Intraductal Component

Banu SARSIK 1, Nisar KARADENİZ 1, Adnan ŞİMŞİR 1, Rahmi AKYOL 1, Kutsal YÖRÜKOĞLU 2, Sait ŞEN 1

1 Department of Pathology, Ege University, Faculty of Medicine, İZMİR, TURKEY
2 Dokuz Eylül University, Faculty of Medicine, İZMİR, TURKEY

DOI: 10.5146/tjpath.2014.01253
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Intraductal carcinoma of prostate has been previously described in radical prostatectomies. It’s rarely encountered in needle biopsies in the absence of infiltrative carcinoma. But, both histogenesis and nomenclature of the lesion is still controversial. Among the pure intraductal carcinoma of prostate cases, a different solid patern was described with smaller nuclei at the center of the ducts. However, there is a lack of information about the association of those cases with acinar prostate adenocarcinoma. Herein, we describe a case of acinar adenocarcinoma with predominant non-neuroendocrine TTF-1 positive small cell intraductal component.

Keywords : Prostate neoplasms, Ductal carcinoma, Thyroid transcription factor-1