Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2007, Vol 23, Num, 1     (Pages: 038-042)

Fine needle aspiration cytology findings in cases diagnosed as oropharyngeal tularemia lymphadenitis (Erratum was published in Vol 24 Number 1, 2008)

Banu DOĞAN GÜN 1, Burak BAHADIR 1, Güven ÇELEBİ 2, Gamze NUMANOĞLU 1, Şükrü Oğuz ÖZDAMAR 1, Gamze MOCAN KUZEY 3

1 Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Patoloji, Anabilim Dalı, ZONGULDAK
2 Zonguldak Karaelmas Üniversitesi Tıp Fakültesi İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji, Anabilim Dalı, ZONGULDAK
3 Hacettepe Üniversitesi Tıp Fakültesi Patoloji, Anabilim Dalı, ANKARA

Viewed: 7301
 - 
Downloaded : 7338

Francisella tularensis is a gram-negative coccobacilus that causes zoonotic disease tularemia. Histopathological examination of lymph node biopsy in tularemia reveals suppurative granulomatous inflammation potentially associated caseous necrosis. Diagnosis is mainly made on the evidence of elevated agglutinating antibodies against F. Tularensis. In this study we aimed to evaluate the cytological features of ulceroglandular tularemia cases and to demonstrate the role of fine needle aspiration cytology in the diagnosis of tularemia.

Fine needle aspiration cytology findings of six cervical lymphadenopaties that had established diagnoses of tularemia both clinically and serologically, were evaluated and the cytomorphological features were described.

All of the cases revealed suppurative inflammation and some caseous necrosis and in four cases epithelioid histiocytes and multinuclear giant cells were observed additionally.

The differential diagnosis of tularemia principally from tuberculosis and other types of bacterial lymphadenitis was made and the place of fine needle aspiration cytology among other diagnostic laboratory tests for tularemia was evaluated.

Keywords : Tularemia, fine needle aspiration, cytology