Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2020, Vol 36, Num, 1     (Pages: 068-072)

Renal Microsporidiosis in Pediatric Bone Marrow Transplant Recipients: A Case Series

Saloni SHAH 1, Sheba Sweetline JACOB 1, Rama MANI 1, Ashok PARAMESWARAN 1, Sunil KUMAR 1, Rajeev A ANNIGERI 2, Raja MAHESH 2, Ramya UPPULURI 3

1 Department of Histopathology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA
2 Department of Nephrology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA
3 Department of Hematology, Apollo Hospitals, CHENNAI, TAMIL NADU, INDIA

DOI: 10.5146/tjpath.2017.01416
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Microsporidiosis is a rare, but emerging opportunistic infection in solid organ transplant and stem cell transplant recipients. Renal involvement in microsporidiosis is very rarely seen in these recipients. We describe two cases of pediatric renal microsporidiosis, diagnosed on renal biopsies, following bone marrow transplantation presenting as severe acute kidney injury. The first patient died, whereas the second survived due to early diagnosis based on high index of suspicion and prompt treatment with Albendazole. We believe these are the first such reported cases of renal microsporidiosis in pediatric bone marrow transplant recipients.

Keywords : Kidney, Microsporidiosis, Opportunistic infection, Pediatrics, Bone marrow transplantation