Astroblastomas are rare tumors of central nervous system and their incidence are 0.45-2.8% among all intracranial gliomas. They occur frequently in children and young adults and in the supratentorial location. Histopathologically differentiation of astroblastomas from ependymomas is difficult. The presented case is a 16 years old female with a recurrent astroblastoma which previously, on two occasions was diagnosed as an ependymoma.