Turkish Journal of Pathology

Türk Patoloji Dergisi

Turkish Journal of Pathology

Turkish Journal of Pathology

2000, Vol 16, Num, 1-2     (Pages: 013-014)

DETECTION OF HPV IN THE TRANSITIONAL CELL CARCINOMA OF THE URINARY BLADDER USING IN SITU HYBRIDIZATION

KAYA Handan 1, KOTİLOĞLU Esin 1, EKİCİOĞLU Gülsün 1, BOZKURT Süheyla Uyar 1, KÜLLÜ Sevgi 1

1 Marmara Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı

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Summary

Recently published data have suggested a link between active human papillomavirus (HPV) infection and the development of bladder cancer. The aim of our study was to detect HPV DNA in of transitional cell carcinomas of the urinary bladder. We analysed a series of 30 formalin-fixed, paraffin-embedded transitional cell carcinomas of the urinary bladder for the presence of HPV DNA by using in situ hybridization technique. HPV DNA was detected in %3,3 (1/30) of the cases.Our results suggest that HPVDNA may play a minor role in the transitional cell carcinoma development in the urinary bladder.
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